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Atomoxetine Review – Is it Safe or Should You Be Concerned?

Atomoxetine: Non-stimulant medication used to treat ADHD. Boosts norepinephrine levels in the brain. Consult your doctor for proper usage and effects.

We looked into Atomoxetine on the basis of its ingredients, customer reviews, and more. Does Atomoxetine really work? Read the Atomoxetine review here!


The main prerequisite to safe medication use is understanding – knowing what a drug does, how it works, and the potential risks it may carry. Hence, this article aims to evaluate atomoxetine’s safety profile and discuss concerns that might arise with its use. Atomoxetine, a common medication for attention deficit hyperactivity disorder (ADHD), has its share of benefits and risks. Before making a decision to use this medication, it’s crucial to delve into the details of what it entails. From its mechanism of action to customer reviews, we will explore various facets of Atomoxetine. After all, is it safe? Or should you be concerned? Read on to find out more.



What is Atomoxetine?

Atomoxetine, often known under the brand name Strattera, is a non-stimulant medication primarily used to treat attention deficit hyperactivity disorder (ADHD). Unlike many other ADHD medications, atomoxetine is not a stimulant but instead falls within the class of drugs known as selective norepinephrine reuptake inhibitors (NRI).

As an NRI, atomoxetine functions by increasing levels of norepinephrine in the brain. Norepinephrine is a neurotransmitter – a chemical messenger that transmits signals throughout the brain and body. This particular neurotransmitter plays a significant role in attention and impulse control, two areas often challenged in individuals diagnosed with ADHD.

Increased levels of norepinephrine can help manage ADHD symptoms by enhancing concentration and reducing impulsivity and hyperactivity. It’s worth noting that while atomoxetine can be an effective component of ADHD management, it does not cure the condition – it aids in symptom management when used consistently as part of a comprehensive treatment plan.

Despite its primary use for ADHD, atomoxetine may also be utilized off-label for certain conditions such as depression and anxiety, underscoring its significant impact on brain chemistry.

How Does Atomoxetine Work?

Understanding the mechanism of action of Atomoxetine is crucial. As a selective norepinephrine reuptake inhibitor, Atomoxetine increases the levels of norepinephrine in the brain.

Norepinephrine is a neurotransmitter that plays an essential role in regulating attention and impulse control.
By selectively inhibiting the reuptake of norepinephrine, Atomoxetine allows more of this neurotransmitter to remain available in the synaptic gap between neurons. This enhances communication between brain cells, improving concentration and reducing impulsive behaviors often associated with ADHD.

It’s worth noting that unlike other ADHD medications, Atomoxetine does not directly impact dopamine levels, a neurotransmitter often linked to pleasure and reward pathways. This key difference sets its mechanism apart from stimulant ADHD medications, which can have addictive properties due to their effect on dopamine.

The role of norepinephrine makes Atomoxetine effective in managing ADHD symptoms, but it also suggests why certain side effects may occur. For more information on norepinephrine’s role in ADHD, you can explore our article on Aanandatol.

This understanding provides insights into how the medication functions and why it may affect individuals differently.


  • Atomoxetine hydrochloride
    Atomoxetine hydrochloride is the active pharmaceutical ingredient in Atomoxetine. It is a selective norepinephrine reuptake inhibitor (SNRI) that works by increasing the levels of norepinephrine in the brain. This neurotransmitter plays a vital role in regulating attention, behavior, and impulse control, making it effective in managing the symptoms of attention-deficit/hyperactivity disorder (ADHD).[1]
  • Microcrystalline cellulose
    Microcrystalline cellulose is an inert substance commonly used in pharmaceutical formulations as a binder, filler, and disintegrant. It helps in maintaining the structural integrity of the medication and assists in its dissolution and absorption in the body.[2]
  • Pregelatinized starch
    Pregelatinized starch is a modified starch that improves the stability and disintegration properties of the medication. It aids in the quick dissolution of the drug and facilitates its release for absorption in the gastrointestinal tract.[3]
  • Sodium lauryl sulfate
    Sodium lauryl sulfate is a surfactant commonly used in pharmaceuticals as an emulsifier and foaming agent. It helps in the uniform distribution of the active ingredient in the formulation and enhances the medication’s appearance and texture.[4]
  • Talc
    Talc is an inactive ingredient used as a glidant and lubricant in pharmaceutical formulations. It prevents the medication from sticking to the manufacturing equipment and improves its flow properties during processing.[5]

Pros and Cons Of Atomoxetine


  • Atomoxetine has been proven to be effective in reducing the symptoms of ADHD, including inattention, hyperactivity, and impulsivity.
  • Unlike stimulant medications, Atomoxetine is not a controlled substance and has a lower risk of abuse or dependence.
  • The effects of Atomoxetine can last throughout the day, requiring only a single daily dose.
  • Atomoxetine can be prescribed to individuals who cannot tolerate stimulant medications or have a history of substance abuse.


  • It may take several weeks of consistent use before experiencing the full benefits of Atomoxetine.
  • Like any medication, Atomoxetine may cause side effects, which should be discussed with a healthcare professional.
  • Atomoxetine may not be suitable for individuals with certain medical conditions or those taking specific medications.
  • Atomoxetine should be used under the guidance of a qualified healthcare professional.

Customer Reviews

Atomoxetine has been a game-changer for me. My productivity at work has improved, and I feel more in control,” shares one user.~ Cindy
On the flip side, others have experienced side effects that impacted their usage of the medication. Complaints often revolve around initial nausea, loss of appetite, or fatigue. However, many note that these side effects lessen over time or with adjusted dosage.
The first week was tough with some nausea and tiredness. But those side effects faded, and now I’m seeing real benefits,” another user explained.~ Lilly
These diverse experiences underscore the importance of individualized treatment plans and close communication with healthcare professionals when using Atomoxetine.


Q: How long does it take for Atomoxetine to work?

A: The effects of Atomoxetine may not be immediately noticeable. It may take several weeks of consistent use to experience the full benefits of the medication.

Q: Is Atomoxetine a stimulant?

A: No, Atomoxetine is not a stimulant. It is a selective norepinephrine reuptake inhibitor (SNRI) that works differently from stimulant medications commonly used to treat ADHD.

Q: Can Atomoxetine be used in children?

A: Yes, Atomoxetine is approved for use in children, adolescents, and adults with ADHD. However, its use in children should be under the supervision of a qualified healthcare professional.

Q: Can Atomoxetine be taken with other medications?

A: It is essential to inform your healthcare provider about all the medications, supplements, or herbal products you are taking before starting Atomoxetine. Some drugs may interact with Atomoxetine, leading to potential adverse effects.


Through this comprehensive atomoxetine review, we’ve delved into various aspects of this ADHD medication. From understanding what atomoxetine is and how it works in our brains, to exploring its ingredients and the pros and cons associated with its use, we’ve provided a thorough exploration of the topic.

We’ve also considered individual experiences through customer reviews, acknowledging that everyone’s body responds differently to medication.

But it’s important to remember:
Consulting with a healthcare professional before starting or changing any medication is essential.
As for the question: “is it safe or should you be concerned?“, the answer isn’t straightforward. While Atomoxetine has proven benefits for managing ADHD symptoms, it also carries potential side effects and risks. Each individual must weigh these benefits against potential drawbacks in consultation with their healthcare provider, taking into account their unique health situation and needs.

Always stay informed and make decisions about your health with care.

The decision to change medication should never be taken lightly. It is important to consider the potential risks and benefits involved. Atomoxetine, for example, has been shown to effectively manage symptoms of ADHD. However, it is also crucial to acknowledge that there are potential side effects and risks associated with its use.

Each person’s health situation is unique, which is why consulting a healthcare provider is essential. They can provide guidance and help individuals weigh the benefits against the potential drawbacks specific to their situation. By staying informed and involving healthcare professionals in decision-making processes, individuals can make well-informed choices about their health.

Ultimately, the safety of changing medication depends on various factors that are specific to each individual. Therefore, it is important to approach such decisions with care and consideration for one’s unique circumstances.

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