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Aripiprazole Review – Is it Safe or Should You Be Concerned?

Aripiprazole: An atypical antipsychotic medication used to treat schizophrenia, bipolar disorder, and major depressive disorder. Balances neurotransmitters in the brain to reduce symptoms.

We looked into Aripiprazole on the basis of its ingredients, customer reviews, and more. Does Aripiprazole really work? Read the Aripiprazole review here!


Aripiprazole is a medication that is primarily used to treat certain mental and mood disorders such as schizophrenia, bipolar disorder, and major depressive disorder. It belongs to a class of drugs known as atypical antipsychotics. Aripiprazole works by affecting certain chemicals in the brain to help restore the balance of neurotransmitters, thereby reducing symptoms associated with these conditions.

What is Aripiprazole?



Aripiprazole, also known by its brand name Abilify, is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia, bipolar disorder, and major depressive disorder in adults and children. It is classified as an atypical antipsychotic, meaning that it works differently from traditional antipsychotic medications.
Aripiprazole is available in various forms, including tablets, orally disintegrating tablets, and extended-release injections. The different formulations offer flexibility in dosing and administration to suit individual patient needs.

How does Aripiprazole work?

The exact mechanism of action of Aripiprazole is not fully understood. However, it is believed to work by acting as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. This unique combination of actions helps to regulate the levels of dopamine and serotonin in the brain, which are neurotransmitters involved in mood and behavior regulation.
By modulating the activity of these neurotransmitters, Aripiprazole can help reduce symptoms of schizophrenia, such as hallucinations and delusions. It can also help stabilize mood and prevent episodes of mania or depression in individuals with bipolar disorder. Additionally, Aripiprazole may be used as an add-on treatment to antidepressant medications to enhance their effectiveness in managing major depressive disorder.


  • Aripiprazole
    Aripiprazole is the active ingredient in Aripiprazole medication. It acts as the main therapeutic component and plays a crucial role in regulating neurotransmitter levels in the brain to manage symptoms of schizophrenia, bipolar disorder, and major depressive disorder.[1]
  • Inactive ingredients
    In addition to the active ingredient, Aripiprazole formulations may contain various inactive ingredients. These inactive ingredients are necessary for the formulation and manufacturing process of the medication. They include fillers, binders, disintegrants, lubricants, and other substances that ensure the stability, consistency, and proper delivery of the medication.[2]
  • Additional ingredients
    Depending on the specific formulation and brand, Aripiprazole may contain additional ingredients such as tablet coatings, capsule shells, or extended-release matrices. These additional ingredients are designed to enhance the pharmacokinetic properties of the medication, allowing for specific release patterns or improved absorption in the body.[3]

Pros and Cons of Aripiprazole


  • Effectively treats symptoms of schizophrenia, bipolar disorder, and major depressive disorder.
  • Can help stabilize mood and reduce hallucinations, delusions, and other psychotic symptoms.
  • May improve overall quality of life for individuals with mental and mood disorders.
  • Available in different formulations, including tablets and extended-release injections, providing options for different patient needs.


  • May cause side effects such as drowsiness, dizziness, weight gain, and restlessness.
  • Can increase the risk of developing certain metabolic conditions, including high blood sugar, high cholesterol, and weight gain.
  • Not suitable for everyone, and individual response to the medication may vary.
  • Requires a prescription and regular monitoring by a healthcare professional.

Side effects of Aripiprazole

Aripiprazole, like any medication, may cause side effects in some individuals. Common side effects include drowsiness, dizziness, headache, blurred vision, restlessness, and weight gain. These side effects are generally mild and may decrease or disappear over time as the body adjusts to the medication. It is important to discuss any persistent or bothersome side effects with a healthcare professional.
Less common but more serious side effects may include changes in mood, suicidal thoughts, irregular heartbeat, difficulty swallowing, uncontrollable movements of the face or body, and allergic reactions. If you experience any of these severe side effects, it is crucial to seek immediate medical attention.

It is important to note that Aripiprazole may increase the risk of developing metabolic conditions, including high blood sugar, high cholesterol, and weight gain. Regular monitoring of metabolic parameters is recommended during treatment with Aripiprazole.

Customer Review

I was taking this medication for less than a week and had major side effects long before I could tell if it actually helped or not.
~ Peter
Love it! Makes me less anxious, and my depression is minimal. It’s like my cloud has lifted. No weight gain as of yet, but I have the energy to be the active woman I’ve always been.


Q: How long does it take for Aripiprazole to start working?

A: The onset of action for Aripiprazole can vary from individual to individual. Some people may start noticing improvements in symptoms within a few days, while for others, it may take several weeks. It is important to follow your healthcare provider’s instructions and continue taking the medication as prescribed, even if you do not see immediate results. Patience and consistency are key to achieving the desired therapeutic effects.

Q: Can Aripiprazole be used in children?

A: Aripiprazole may be prescribed to children for certain approved indications, such as schizophrenia and bipolar disorder. The dosing and safety considerations may differ for pediatric patients, and it is essential to consult with a healthcare professional to determine the appropriateness of Aripiprazole for a child.

Q: Can I stop taking Aripiprazole suddenly?

A: No, it is not recommended to stop taking Aripiprazole abruptly without consulting your healthcare provider. Sudden discontinuation may lead to withdrawal symptoms or a relapse of symptoms. Your healthcare provider will guide you on the appropriate way to stop or adjust the dosage of Aripiprazole.

Q: Can Aripiprazole interact with other medications?

A: Aripiprazole has the potential to interact with certain medications, including other antipsychotics, antidepressants, and medications that affect the central nervous system. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid any potential drug interactions. They can evaluate the potential interactions and make adjustments to your treatment plan if necessary.


Aripiprazole is an atypical antipsychotic medication used to treat schizophrenia, bipolar disorder, and major depressive disorder. It works by affecting the balance of neurotransmitters in the brain, helping to reduce symptoms associated with these conditions. While it can be effective in managing mental and mood disorders, it is essential to be aware of the potential side effects and discuss any concerns with a healthcare professional. Aripiprazole should always be used under the guidance of a qualified healthcare provider, who can monitor its effectiveness and make any necessary adjustments to ensure the best outcome for the patient.

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